Infusion Pump Flow Rates In Central Venous Catheters: Thrombus Reflux And Aspiration Clot

Aggressive infusion pump flow rates can lead to central venous catheter (CVC) occlusion resulting from thrombus reflux into the CVC lumen. 
 Methods: A single-center prospective comparative study was performed, including all consecutive cases of events in hematology oncology patients using a (Hickman® nº7) since August 2018 September 2019 (Phase 1), and October 2020 2) at Onco-Hematology Department Portuguese Institute Oncology (Porto). Two phases were described:
 Phase 1: Observational period platinum-based regime (DHAP) undergoing continuous rate ≥ 200 mL/hr.
 2: Intervention ≤ Results: Overall, 39 DHAP regimens reported with total number 43 occlusions identified (phase 1, n=28 vs phase 2, n=15). Occlusion risk associated between higher 1 n=11 n=3, RR 3.313 [1.010 13.863], ≤0.05). When aspiration clot (n=5) identified, always removed. No observed 2. Conclusion: increase lumen clot.